Vinpocetine powder

November 5, 2020

Cofttek is the best Vinpocetine powder manufacturer in China. Our factory has a complete production management system (ISO9001 & ISO14001), with a monthly production capacity of 340kg.

Status: In Mass Production
Unit: 1kg/bag, 25kg/Drum

Vinpocetine powder Specifications

Name: Vinpocetine
CAS: 42971-09-5
Purity 98%
Molecular Formula: C22H26N2O2
Molecular Weight: 350.454 g/mol
Melt Point: 147-149° C
Chemical name: AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate,
Synonyms: Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
Elimination Half Life: 2.54 +/- 0.48 hours
Solubility: Soluble in DMSO, Methanol, Water
Storage Condition: 0 – 4 C for short term (days to weeks), or -20 C for long term (months)
Application: Vinpocetine is a compound from the Periwinkle plant that is used as a cognitive protective and anti-aging agent. One of the more common of the nootropics, Vinpocetine may enhance blood flow and is touted to increase memory; this latter claim has not been investigated.
Appearance: White powder


Vinpocetine (42971-09-5) NMR Spectrum

Vinpocetine (42971-09-5) - NMR Spectrum

If you need COA, MSDS, HNMR for each batch of product and other information, please contact our marketing manager.


What is Vinpocetine (42971-09-5)?

Vinpocetine is a synthetic alkaloid derived from the periwinkle plant (specifically, synthesized from the molecule known as ‘vincamine’) that appears to have a track record of usage in European countries for the treatment of cognitive decline, stroke recovery, and epilepsy. Vinpocetine is also commonly used as a nootropic compound in the hopes that it may promote memory formation.


Vinpocetine powder (42971-09-5) benefits

Vinpocetine is not fully absorbed, but what is absorbed peaks in the blood rapidly and easily enters the brain where it can exert its functions. The properties that appear to apply to oral vinpocetine supplementation include neuroprotection (against toxins and excess stimulation) and reducing neural inflammation, whereas the cognitive enhancement effect does not appear to be well supported by evidence at this point in time. While vinpocetine does appear to be effective in preventing toxins or stressors from causing amnesia, it is not yet demonstrated to inherently improve memory formation.

Vinpocetine also appears to have some efficacy against cognitive decline, but the amount of literature on this topic is much less than other drugs tested for this purpose (CDP-Choline or Alpha-GPC in particular). At least one study has noted an improvement in reaction time with a 40mg tablet of vinpocetine, which may be one of the only practically relevant improvements for healthy persons at this moment in time.

Infusions of vinpocetine do appear to enhance blood flow to the brain without inherently modifying pressure systemically, and this is thought (but not shown) to apply to oral ingestion. This would potentially reduce headaches caused by excessive pressure, and is in accordance with the traditional usage of the periwinkle plant (to reduce headaches).


Vinpocetine (42971-09-5) Application?

The mechanisms of vinpocetine are numerous. It appears to interact with several ion channels (sodium, potassium, and calcium) while tends to result in suppressive effects on neurotransmitter release and neuroprotection when dopamine or glutamate are suppressed (these two, when unnecessarily stimulated by toxins, can cause oxidative damage). It also interacts with alpha adrenergic receptors and the TPSO receptor, and while the exact benefit of these receptor interactions are not clear they are probably relevant since they occur at the same concentrations that the ion channel interactions do.

Vinpocetine is also a PDE1 inhibitor, which is a mechanism that is both cardioprotective and cognitive enhancing. Unfortunately, this inhibition occurs at a fairly large dose and may not apply to standard supplemental dosages of vinpocetine.

Similar to PDE1, an antidopaminergic potential of vinpocetine and direct inhibition of glutaminergic receptors both appear to occur at very high concentrations in vitro and may not be relevant to standard supplementation.


Vinpocetine (42971-09-5) Dosage

Vinpocetine is taken in the daily dosage range of 15-60mg, divided into three daily doses with meals. The standard low dose is 5mg at each of these three meals, with 20mg at each meal being seen as the higher end of efficacy. These doses are taken for the purposes of neuroprotection, enhancing cerebral blood flow, and reducing the rate of cognitive decline.

Doses in the higher end of that range (30-45mg acute dosages) may be useful for promoting cognition and memory formation in otherwise healthy persons, but there is not a lot of evidence looking at this claim.

Warning: for pregnant women, the equivalent of doses abouve 10 mg/d have been linked to fetal toxicity in animal studies. 10 mg/d may also be risky, especially when taking throughout an entire pregnancy.


Vinpocetine powder for sale(Where to Buy Vinpocetine powder in bulk)

Our company enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time. We also focus on value-added services. We are available for service questions and information to support your business.

We are an professional Vinpocetine powder supplier for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.


  1. Abdel-Salam OME. Vinpocetine and piracetam exert antinociceptive effect in visceral pain model in mice. Pharmacol Rep. 2006;58(5):680-691.17085860
  2. Akopov SE, Gabrielian ES. Effects of aspirin, dipyridamole, nifedipine and Cavinton which act on platelet aggregation induced by different aggregating agents alone and in combination. Eur J Clin Pharmacol. 1992;42(3):257-259.1577042
  3. Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine and pyritinol: a new model for blood rheological modulation in cerebrovascular disorders—a randomized controlled clinical study. Biomed Res Int. 2014;2014:324307.25548768.