Showing 601–612 of 630 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|1246560-33-7||VS-5584 (SB2343) (1246560-33-7)||
VS-5584 (SB2343) is a novel and highly selective dual PI3K/mTOR inhibitor for the treatment of cancer with IC50 of 3.4 nM and 2.6-21 nM, resp...
|1135242-13-5||VU0357017 hydrochloride (1135242-13-5)|
VU0357017, also known as CID 25010775, is a subtype-selective M1 muscarinic acetylcholine allosteric agonist.
VU 0361737 is a selective positive allosteric modulator at mGluR-4 (EC50 values are 240 and 110 nM at human and rat receptors respectively)...
VU 0364770 is a positive allosteric modulator(PAM) of mGlu4 with EC50 of 1.1 μM, exhibits insignificant activity at 68 other receptors, inclu...
VX-702 is a highly selective inhibitor of p38α MAPK, 14-fold higher potency against the p38α versus p38β. Phase 2. VX-702, one of a series of...
VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ̷...
WAY-262611 is a wingless β-Catenin agonist that increases bone formation rate; with EC50 of 0.63 uM in TCF-Luciferase assay.
WEHI-539, has high affinity (subnanomolar) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival ac...
Wnt-C59 (C59) is a PORCN inhibitor for Wnt3A-mediated activation of a multimerized TCF-binding site driving luciferase with IC50 of 74 pM.
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2...
|1144068-46-1||WYE125132 (WYE-132) (1144068-46-1)||
WYE125132, also known as WYE-132, is highly potent, ATP-competitive, and specific inhibitor of mTOR kinase with IC50 value of 0.19±0.07nmol/L...
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