Showing 25–36 of 630 results

CAS NO. PRODUCT NAME OVERVIEW
    467214-20-6 Alvespimycin (17-DMAG; KOS-1022; NSC 707545) (467214-20-6)

    Alvespimycin (17-DMAG; KOS-1022; NSC 707545) is a potent, water-soluble HSP90 inhibitor with IC50 of 62 nM, and promising therapeutic agent f...

    164178-33-0 AM630 (164178-33-0)

    Iodopravadoline, also known as AM630, is an inverse agonist at the human cannabinoid CB1 receptor. Iodopravadoline has been found to attenuat...

    1173699-31-4 AMG-337 (1173699-31-4)

    AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor. AMG-337 is a potent and highly selective...

    1361224-53-4 AMG-3969 (1361224-53-4)

    AMG-3969 is a potent, metabolically stable Glucokinase (GK)-GKRP (GK regulatory protein) disruptor with IC50 of 4 nM, does not block the GK b...

    913376-83-7 AMG-458 (913376-83-7)

    AMG 458 is a potent c-Met inhibitor with Ki of 1 nM ~ 2.0 nM. AMG-458 was found to significantly inhibit tumor growth in the NIH3T3/TPR-Met a...

    945595-80-2 AMG-900 (945595-80-2)

    AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold select...

    1002304-34-8 AMG208 (1002304-34-8)

    AMG 208 is a small molecule inhibitor of c-Met which is a well-characterized receptor tyrosine kinase expressed on the surface of epithelial ...

    1608125-21-8 AMG319 (1608125-21-8)

    AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks, with potential clinical anti-i...

    659730-32-2 AMG517 (659730-32-2)

    AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM...

    857876-30-3 AMG706 (857876-30-3)

    Motesanib (AMG-706), is an orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib ...

    1401033-86-0 AMG925 (1401033-86-0)

    AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively..

    942398-84-7 Amiselimod (942398-84-7)

    Amiselimod hydrochloride is a novel sphingosine 1-phosphate receptor-1 (S1P1) modulator, designed to reduce the bradycardia effects associate...

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