Showing 13–24 of 630 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
AC710 is a potent, orally active, and selective platelet-derived growth factor receptor-family kinase inhibitor with potential anticancer act...
|870281-34-8||Acalisib (GS-9820) (870281-34-8)||
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide...
|30827-99-7||AEBSF HCL (30827-99-7)||
AEBSF or 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride is a water-soluble, irreversible serine protease inhibitor with a molecular w...
|497839-62-0||AEE788 (NVP-AEE788) (497839-62-0)||
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt...
|439081-18-2||Afatinib (BIBW2992) (439081-18-2)||
Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor...
|1047634-63-8||Afuresertib (GSK2110183) (1047634-63-8)||
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Aktinhibitor with IC50s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 r...
AG-1024 (Tyrphostin) inhibits IGF-1R autophosphorylation with IC50 of 7 μM, is less potent to IR with IC50 of 57 μM and specifically distingu...
AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50s are 29 nM and 14 n...
AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR….
|133550-30-8||AG490 (Tyrphostin) (133550-30-8)||
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3...
|1256580-46-7||Alectinib (CH5424802) (1256580-46-7)||
Alectinib (CH5424802) is a potent ALK inhibitor with IC50 of 1.9 nM in cell-free assays, sensitive to L1196M mutation and higher selectivity ...
|1345847-93-9||Altiratinib (DCC-2701) (1345847-93-9)||
Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, ce...
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