Alpha GPC (28319-77-9) video
Alpha GPC Specifications
|Purity||50% non- hygroscopic powder；50%&99% powder；85% liquid|
|Molecular Weight:||257.223 g/mol|
|Chemical name:||Alpha GPC; Choline Alfoscerate; Alpha Glycerylphosphorylcholine|
|Synonyms:||(R)-2,3-dihydroxypropyl (2-(trimethylammonio)ethyl) phosphate; sn-Glycero-3-phosphocholine|
|Half Life:||4-6 hours|
|Solubility:||Soluble in DMSO, Methanol, Water|
|Storage Condition:||0 – 4 C for short term (days to weeks), or -20 C for long term (months)|
|Application:||Alpha GPC (Choline Alfoscerate) is a phospholipid;precursor in choline biosynthesis and an intermediate in catabolic pathway of phosphatidylcholine. Alpha GPC is used as an Nootropic.|
What is Alpha GPC (28319-77-9)?
Alpha GPC (alpha glycerophosphocholine), like citicoline, may also aid neuroprotective activity. It’s a compound composed of glycerophosphate and choline. Alpha GPC is a natural compound that can also work well with other nootropics. Alpha GPC works fast and helps deliver choline to the brain and actually increases the production of acetylcholine along with cell membrane phospholipids. It’s possible the compound may also increase the release of dopamine and calcium.
Alpha GPC (28319-77-9) benefits
Alpha GPC brings with it a number of possible benefits, one of the most important being the possibility of improving brain health and cognition. It may be possible for Alpha GPC to improve memory formation and enhance learning ability. The possible memory enhancement benefits from alpha GPC may actually restore memory, but only in certain situations. Alpha GPC can also raise dopamine levels, which benefits brain function significantly.
Alpha GPC is a water-soluble phospholipid metabolite that serves as a precursor for acetylcholine (ACh) and phosphatidylcholine (PC) biosynthesis throughout the body. Due to its activity profile and ability to cross the blood-brain barrier, it appears to be the most effective cholinergic compound, when compared to choline and CDP-choline, and is well tolerated. Research suggests that alpha-GPC supports many roles within the CNS including: sensory stimuli response, supporting learning and memory, and may play a role in healthy mood. Owing to the provision of glycerophosphate, alpha-GPC also appears to support the structure and function of neural tissues and cellular membranes, and may play a role in supporting healthy brain function during injury recovery.
Alpha GPC (28319-77-9) Mechanism Of Action?
Alpha GPC prompts the cholinergic system that takes care of cognitive aspects like memory recall and thinking. It is a preferred source of choline which acts as a precursor to the neurotransmitter acetylcholine.
Acetylcholine is found widely throughout the brain and body and is responsible for many chemical messages that we send and receive. And it isvery well-known for learning as well as for muscle contraction thus forming the brain-brawn link. Alpha GPC works fast and helps deliver choline to the brain and actually increases the production of acetylcholine. By providing your brain with more choline it can convert that to acetylcholine and contribute to a host of downstream effects. Primarily, acetylcholine is utilized by the hippocampus to create memories.
Acetylcholine works in a variety of ways to support your working memory. It can also enhance your linguistic skills, your capacity to reason and use logic, as well as your creativity. The same is also crucial for memory, coordination, and mobility. Levels of this neurotransmitter naturallydecline with age. To make sure that you have enough of this brain chemical available to meet the demands of your cognitive activity, you needto keep levels up.
Alpha GPC (28319-77-9) Application
Alpha-GPC is a chemical released when a fatty acid found in soy and other plants breaks down. It is used as medicine.
In Europe alpha-GPC is a prescription medication for the treatment of Alzheimer’s disease. It is available in two forms; one is taken by mouth, and the other is given as a shot. In the United States alpha-GPC is onlyavailable as a dietary supplement, mostly in products promoted to improve memory.
Other uses for alpha-GPC include treatment of various kinds of dementia, stroke, and “mini-stroke” (transient ischemic attack, TIA). Alpha-GPC is also used for improving memory, thinking skills, and learning.
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- Ricci A, Bronzetti E, Vega JA, Amenta F. Oral choline alfoscerate counteracts age-dependent loss of mossy fibres in the rat hippocampus. Mech Ageing Dev. 1992;66(1):81-91. PubMed PMID: 1340517.
- Amenta F, Ferrante F, Vega JA, Zaccheo D. Long term choline alfoscerate treatment counters age-dependent microanatomical changes in rat brain. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Sep;18(5):915-24. PubMed PMID: 7972861.
- Amenta F, Del Valle M, Vega JA, Zaccheo D. Age-related structural changes in the rat cerebellar cortex: effect of choline alfoscerate treatment. Mech Ageing Dev. 1991 Dec 2;61(2):173-86. PubMed PMID: 1824122.