Noopept (157115-85-0)

May 7, 2021

Cofttek is the best Noopept powder manufacturer in China. Our factory has a complete production management system (ISO9001 & ISO14001), with a monthly production capacity of 600kg.

 


Status: In Mass Production
Unit: 1kg/bag, 25kg/Drum

Noopept (157115-85-0) Specifications

Name: Noopept
CAS: 157115-85-0
Purity 98%
Molecular Formula: C17H22N2O4
Molecular Weight: 318.37 g/moll
Melt Point: 94.0 to 98.0 °C
Chemical name: ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate
Synonyms: Noopept;ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate;N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester;Ethyl 1-(phenylacetyl)-L-prolylglycinate;noopept powder;Nootropic GVS-111;(S)-ethyl 2-(1-(2-phenylacetyl)pyrrolidine-2-carboxaMido)acetate;SGS 111
InChI Key: PJNSMUBMSNAEEN-AWEZNQCLSA-N
Half Life: Noopept half-life is just 60 to 90 minutes, which means that an average person can fully process half of the dose in that period of time.
Solubility: Soluble in DMSO (25 mg/ml)
Storage Condition: 0 – 4 C for short term (days to weeks), or -20 C for long term (months)
Application: Noopept is a popular cognitive-enhancing supplement in the nootropic community. The human studies have shown promising results, with potential application in the treatment of Alzheimer’s disease.
Appearance: white to beige powder

 

What is Noopept (157115-85-0)?

Noopept is the brand name for N-phenylacetyl-L-prolylglycine ethyl ester; a synthetic nootropic compound often erroneously said to be part of the racetam class of nootropics (it lacks a 2-oxo-pyrollidine nucleus so is not a racetam). In Russia, where Noopept was first synthesized, it is sometimes referred to as GSV-111.

Noopept was created in 1996. Its structure is based on that of cycloprolylglycine; an endogenous neuropeptide. Cycloprolylglycine is known to promote the expression of Brain Derived Neurotrophic Factor in the brain. Researchers therefore posited that a nootropic based on cycloprolylglycine would have similar effects, and that is exactly what is claimed about Noopept.

Although it isn’t a racetam, Noopept is structurally similar to Piracetam. Noopept is actually a dipeptide conjugate of Piracetam. The two molecules are said to have very similar effects, with Noopept being the much more potent of the two nootropics by weight.

 

Noopept (157115-85-0) benefits

The benefits associated with Noopept are extensive and varied. This is unsurprising given that it both potentiates acetylcholine and increases levels of NGF and BDNF.

Here is a list of the benefits typically associated with Noopept:

  • Improved memory function
  • Enhanced attention, focus and concentration
  • Increased wakefulness
  • Promotes neuroplasticity and growth of new brain tissues
  • Reduces oxidative stress and promotes brain health
  • Reduces anxiety and promotes excitability

All of these effects would result from increasing acetylcholine receptor numbers on the neuronal membrane and from increasing NGF/BDNF levels over the long-term. The effect that elevating neuropeptide has on cognition is dramatic, and the short-term effect of potentiating acetylcholine is certainly noticeable. The combined effect of these two mechanisms would essentially be complete brain optimization, with every aspect of brain function improved in some way.

 

Noopept (157115-85-0) uses?

Noopept is a popular cognitive-enhancing supplement in the nootropic community. Noopept is primarily used for increasing acetylcholine signaling, increasing the expression of BDNF and NGF, protecting from glutamate toxicity, and increasing inhibitory neurotransmission in the brain. These are proposed mechanisms of action based on preclinical studies.

 

Noopept (157115-85-0) Dosage

Noopept dosing can be confusing, especially for beginners, but here’s a quick and easy guide to help you out.

Remember, while Noopept is often compared to Piracetam, it’s actually up to 1000 times more potent than Piracetam!

With that said, don’t use the same amount that you would normally do with Piracetam or even with other nootropics with similar effects.

As a general rule, you should also spread out one dose throughout the day and take a break after every two months for safety purposes.

 

  • Oral Dosage

The recommended dosage for an adult is 10-30 mg, depending on your weight. However, it’s always best to start with just 10 mg to assess the effect on your body.

After all, you can always increase the dose afterward.

Capsules come in a variety of sizes, so be sure to check the label properly before purchasing a bottle.

Take only the minimum amount you need for your safety. This will also help prevent you from building a tolerance to the drug.

 

  • Sublingual Dosage

For sublingual dosage, you should start a bit lower, at around 5 mg.

Since it has quicker and more potent results, you should observe how you react to this method before increasing to the standard 10 mg dose.

It’s very important to accurately measure the amount of powder you need. High doses could lead to problematic Noopept side effects, so be extra careful!

 

  • Snorting Powder Dosage

Similar to sublingual dosage, snorting powder dosage should be quite low.

While it’s generally safe to take 10-30 mg in any form, Noopept may cause headaches, fatigue, and nausea, so always err on the side of caution.

 

  • Megadose

If a typical dose is 10 to 30 milligrams, a Noopept megadose is a whopping 50 to 100 milligrams. Some people even take amounts greater than 100 mg!

A megadose is used when you want to see a dramatic improvement in your memory, learning, intelligence, and overall cognitive skills.

This should only be done once a week at most, as continuous use could make it less effective in the long-term.

Additionally, this can be extremely dangerous for some people, so make sure you’re fully aware of your own tolerance level before attempting this.

 

Noopept powder for sale (Where to Buy Noopept powder in bulk)

Our company enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time. We also focus on value-added services. We are available for service questions and information to support your business.

We are an professional Noopept powder supplier for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

 

References

[1] Ostrovskaya RU, Gudasheva TA, Zaplina AP, Vahitova JV, Salimgareeva MH, Jamidanov RS, Seredenin SB. Noopept stimulates the expression of NGF and BDNF in rat hippocampus. Bull Exp Biol Med. 2008 Sep;146(3):334-7. doi: 10.1007/s10517-008-0297-x. PMID: 19240853.

[2] Neznamov GG, Teleshova ES. Comparative studies of Noopept and piracetam in the treatment of patients with mild cognitive disorders in organic brain diseases of vascular and traumatic origin. Neurosci Behav Physiol. 2009 Mar;39(3):311-21. doi: 10.1007/s11055-009-9128-4. PMID: 19234797.

[3] Murzina, G.B., Pivovarov, A.S. Modulation of the Acetylcholine-Induced Input Current by Noopept in Helix Lucorum Neurons. BIOPHYSICS 64, 393–399 (2019).

[4] Neznamov, G. G.; Teleshova, E. S. (2009). “Comparative studies of Noopept and piracetam in the treatment of patients with mild cognitive disorders in organic brain diseases of vascular and traumatic origin”. Neuroscience and Behavioral Physiology. 39 (3): 311–321.

[5] Tardner, P (2020). “Finding the optimal dosage fornootropic agent Noopept: An analysis of available literature” (PDF). International Journal of Environmental Science and Technology.