Pyrroloquinoline Quinone disodium salt (122628-50-6)
Pyrroloquinoline Quinone disodium salt Specifications
|Name:||Pyrroloquinoline Quinone disodium salt powder|
|Molecular Weight:||374.17 g/mol|
|Chemical name:||Disodium 4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylate|
Methoxatin disodium salt
Methoxatin (disodium salt)
Pyrroloquinoline quinone disodium salt
|Solubility:||Soluble in DMSO, Methanol, Water|
|Storage Condition:||0 – 4 C for short term (days to weeks), or -20 C for long term (months)|
|Application:||PQQ protects cells in the body from oxidative damage and supports the metabolism of energy and healthy aging. It is also considered a novel cofactor with antioxidant and B vitamin-like activity. It promotes cognitive health and memory by combatting mitochondrial dysfunction and protecting neurons from oxidative damage.|
|Appearance:||red brown powder|
Pyrroloquinoline Quinone (122628-50-6) NMR Spectrum
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What is Pyrroloquinoline Quinone disodium salt (122628-50-6)?
Pyrroloquinoline Quinone disodium salt is a bit of a mouthful, so most people prefer to use the abbreviation PQQ disodium salt or PQQ. It’s also called methoxatin. So what is PQQ disodium salt? PQQ disodium salt is the disodium form of PQQ, PQQ was thought to be a type of vitamin, PQQ naturally exists in most vegetable foods, fruits, and vegetables (trace), and relatively high levels of PQQ can be detected in fermented soybean products, such as kiwifruit, lychee, green beans, tofu, rapeseed, mustard, green tea (camellia), green pepper, spinach, etc. Pyrroloquinoline quinone disodium salt (pqq) complex, the best form of PQQ is powder form. but many people choose to incorporate it in their diets through PQQ supplements.
Pyrroloquinoline Quinone disodium salt (122628-50-6) benefits
The benefits of taking PQQ disodium salt powder may include:
Since mitochondria produce energy for the cell, and PQQ helps mitochondria work more efficiently, there is an overall increase of energy within your cells. The unused cellular energy is transferred to other parts of your body. If you struggle to have energy to make it through the day, or you experience fatigue or lethargy, this added boost of energy from PPQ will be important to you. One study found that participants who reported having problems with their energy, experienced a noticeable decrease in their fatigue after taking PQQ. If you’re looking for a boost to your energy, PQQ may help with that.
Participants in the study mentioned above also reported that they were able to sleep better after taking PQQ for 8 weeks. Prior to beginning the study, these patients had been experiencing sleeping problems. PQQ seems to reduce the amount of cortisol, or stress hormone, within patients and improve their sleep. While PQQ’s benefits to sleep haven’t been studied thoroughly, these initial results seems promising.
With a reduced amount of stress, researchers have begun to see improvements to memory. In this case, the combination of PQQ and CoQ10 may lead to memory enhancement and promoting cognitive health. CoQ10, like PQQ, is another nutrient that can offer support to the body’s mitochondria. Many patients often look at PQQ and CoQ10 as an either/or option, but taking one and ignoring the other may result in missing out on some big benefits.
Pyrroloquinoline Quinone disodium salt (122628-50-6) Mechanism Of Action?
Pyrroloquinoline quinone (PQQ) is a small quinone molecule, which has a redox effect, can reduce oxidant (antioxidant); it then is recovered into the active form by glutathione. It seems relatively stable because it can undergo thousands of cycles before depletion, and it is new because it is related to the protein structure of cells (some antioxidants, main carotenoids such as beta-carotene and astaxanthin, are located in specific areas of cells, where they play more antioxidant roles proportionally). Because of proximity, PQQ seems to play a role near proteins such as carotenoids on cell membranes.
Perhaps most notable is the effect of PQQ on mitochondria, which provide energy (ATP) and regulate cell metabolism. Researchers have extensively observed the impact of PPQ on mitochondria and found that PQQ can increase the number of mitochondria and even improve the efficiency of mitochondria. This is an important reason why PPQ is so useful. Enzymes containing PQQ are known as glucose dehydrogenase, a quinoa protein that is used as a glucose sensor.
Pyrroloquinoline Quinone disodium salt (122628-50-6) Application
Pyrroloquinoline quinone (henceforth PQQ) is a small quinone molecule which has the ability to be a REDOX agent, capable of reducing oxidants (an antioxidant effect) and then being recycled by glutathione back into an active form. It appears to be quite stable as it can undergo several thousand cycles before being used up, and it is novel since it associates with protein structures inside the cell (some antioxidants, mostly notably carotenoids like β-carotene and astaxanthin, are located at specific areas of a cell where they exert proportionally more antioxidant effects due to proximity; PQQ seems to do this near proteins like carotenoids do so at the cell membrane).
Pyrroloquinoline Quinone disodium salt powder for sale(Where to Buy Pyrroloquinoline Quinone disodium salt powder in bulk)
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- Ameyama M, Matsushita K, Ohno Y, Shinagawa E, Adachi O (1981). “Existence of a novel prosthetic group, PQQ, in membrane-bound, electron transport chain-linked, primary dehydrogenases of oxidative bacteria”. FEBS Lett. 130 (2): 179–83. doi:10.1016/0014-5793(81)81114-3. PMID 6793395.
- Haft DH (2011). “Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners”. BMC Genomics. 12: 21. doi:10.1186/1471-2164-12-21. PMC 3023750. PMID 21223593.
- Ameyama M, Matsushita K, Shinagawa E, Hayashi M, Adachi O (1988). “Pyrroloquinoline quinone: excretion by methylotrophs and growth stimulation for microorganisms”. BioFactors. 1 (1): 51–3. PMID 2855583.