β-Nicotinamide Mononucleotide (1094-61-7) Manufacturer - Cofttek

β-Nicotinamide Mononucleotide (1094-61-7)

April 7, 2020

Nicotinamide Mononucleotide, also known as (“NMN” and “β-NMN”) is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH).

 


Status: In Mass Production
Unit: 25kg/Drum

β-Nicotinamide Mononucleotide (1094-61-7) video

 

β-Nicotinamide Mononucleotide (NMN) Specifications

Name: β-Nicotinamide Mononucleotide (NMN)
CAS: 1094-61-7
Purity 98%
Molecular Formula: C11H15N2O8P
Molecular Weight: 334.2208 g/mol
Melt Point: >96°C
Chemical name: ((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate
Synonyms: Nicotinamide Mononucleotide; NMN; β-NMN; β-Nicotinamide mononucleotide
InChI Key: DAYLJWODMCOQEW-TURQNECASA-N
Half Life: N/A
Solubility: Soluble in DMSO, Methanol, Water
Storage Condition: 0 – 4 C for short term (days to weeks), or -20 C for long term (months)
Application: Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism, and gene expression in the body.
Appearance: White powder

 

What is β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7?

Nicotinamide Mononucleotide, also known as (“NMN” and “β-NMN”) is a nucleotide derived from ribose and nicotinamide Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). Because NADH is a cofactor for processes inside mitochondria, for sirtuins, and for PARP, NMN has been studied in animal models as a potential neuroprotective and anti-aging agent.

 

β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 benefits

Anti-aging research has shown that supplementation with NMN, a key NAD+ intermediate, is effective at mitigating age-associated metabolic decline and slowing the progression of a multitude of age-related diseases. NMN has beneficial effects on the production of energy at the cellular level, improves tolerance to glucose, reduces inflammation, helps preserve the circulatory system, repairs DNA, and has beneficial effects on the preservation of cognitive function. NMN has also shown potential as a therapeutic agent against neurodegenerative disorders typical of old age. Supplementation with NMN may be of benefit in preserving endurance and mobility. Preserving the functions of these diverse systems across the body promotes health and longevity and significantly improves quality of life as aging progresses.

 

β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 Mechanism Of Action?

β-Nicotinamide Mononucleotide (NMN) is an intermediate of NAD+ biosynthesis produced from nicotinamide through nicotinamide phosphoribosyltransferase (NAMPT) and also referred to as NMN or nicotinamide ribotide. In recent studies of NMN applications to prevention and diagnosis of age-dependent diseases such as diabetes, neurodegenerative disorder, cardiac disease etc, it has become one of hottest biomarkers on discussion for anti-aging, lately.

 

β-Nicotinamide Mononucleotide (NMN) CAS 1094-61-7 Application

β-Nicotinamide Mononucleotide (NMN) has beneficial effects on metabolism throughout the body, including positive effects in skeletal muscle, liver function, bone density, eye function, insulin sensitivity, immune function, body weight, and activity levels.

 

β-Nicotinamide Mononucleotide (NMN) powder for sale(Where to Buy β-Nicotinamide Mononucleotide (NMN) powder in bulk)

Our company enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time. We also focus on value-added services. We are available for service questions and information to support your business.

We are an professional β-Nicotinamide Mononucleotide (NMN) powder supplier for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

 

References

  • Kiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 May 29. doi: 10.1007/s11357-019-00074-2. PubMed PMID: 31144244.
  • Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, Yang X, Park J, Hopkin RJ, Coleman MP, Zhai RG, Stottmann RW. Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. Exp Neurol. 2019 May 25:112961. doi: 10.1016/j.expneurol.2019.112961.PubMed PMID: 31136762.
  • Grozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME, Imai SI. Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 2019 Jan;1(1):47-57. doi: 10.1038/s42255-018-0009-4. Epub 2019 Jan 7. PubMed PMID: 31131364; PubMed Central PMCID: PMC6530925.