Showing 1–12 of 362 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase...
(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2),binding to all bromodomains of the BET family, but not to brom...
A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over oth...
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 value...
A66 is a highly specific and selective p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoform...
A 77-01 is potent TGF-βRI (ALK-5) inhibitor (IC50 = 34 nM). Inhibits TGF-β transcriptional activation. Inhibits TGF-β-induced proliferation o...
A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with I...
|714971-09-2||AC480 (BMS-599626) (714971-09-2)||
AC480, also known as BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced So...
|870281-34-8||Acalisib (GS-9820) (870281-34-8)||
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide...
|497839-62-0||AEE788 (NVP-AEE788) (497839-62-0)||
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt...
|439081-18-2||Afatinib (BIBW2992) (439081-18-2)||
Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor...
|1047634-63-8||Afuresertib (GSK2110183) (1047634-63-8)||
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Aktinhibitor with IC50s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 r...
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