Showing 1–12 of 630 results

CAS NO. PRODUCT NAME OVERVIEW
    856925-71-8 (-)-Blebbistatin (856925-71-8)

    (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase...

    1268524-70-4 (+)-JQ1 (1268524-70-4)

    (+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2),binding to all bromodomains of the BET family, but not to brom...

    5142-23-4 3-Methyladenine (3-MA) (5142-23-4)

    3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase).It can protect cerebellar granule cells from apoptos...

    1668553-26-1 A-1210477 (1668553-26-1)

    A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over oth...

    1527503-11-2 A-366 (1527503-11-2)

    A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC₅₀ = 3.3 nM). It displays >1000-fold selectivity for...

    552325-73-2 A-674563 (552325-73-2)

    A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 value...

    844499-71-4 A-769662 (844499-71-4)

    A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.A-769662 displays selectivity towards β...

    934162-61-5 A-966492 (934162-61-5)

    A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.

    1166227-08-2 A66 (1166227-08-2)

    A66 is a highly specific and selective p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoform...

    607737-87-1 A77-01 (607737-87-1)

    A 77-01 is potent TGF-βRI (ALK-5) inhibitor (IC50 = 34 nM). Inhibits TGF-β transcriptional activation. Inhibits TGF-β-induced proliferation o...

    909910-43-6 A83-01 (909910-43-6)

    A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with I...

    714971-09-2 AC480 (BMS-599626) (714971-09-2)

    AC480, also known as BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced So...

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