Showing 1–12 of 42 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|497839-62-0||AEE788 (NVP-AEE788) (497839-62-0)||
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt...
|439081-18-2||Afatinib (BIBW2992) (439081-18-2)||
Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor...
AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR….
|133550-30-8||AG490 (Tyrphostin) (133550-30-8)||
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3...
Anlotinib, also known as AL3818, is a receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic and anti-angiogenic activities...
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.-VEGFR inhibitor…
Axitinib is an oral, potent, and selective inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3. Axitinib is markete...
AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. AZD3759 is a...
|848942-61-0||AZD8931 (Sapitinib) (848942-61-0)||
Sapitinib is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. Sapitinib has been used in trials studying th...
|861875-60-7||BAW2881 (NVP-BAW2881) (861875-60-7)||
BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to in...
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with...
- PARP&Proteasome (22)
- Akt &GSK-3 (37)
- ATM&ATR (35)
- Bcl-2&P53 (11)
- c-Kit&c-Met (25)
- CDK&Aurora kinase (21)
- Chk&Rho (8)
- HDAC&PLK (0)
- HER2&FLT3 (13)
- IGF-1R&ALK (21)
- JAK&Bcr-Abl (4)
- MEK&P38 MAPK (22)
- PDGFR&FGFR (20)
- PI3K&mTOR (55)
- PKC&ROCK (21)
- Raf&HSP (0)
- S6 kinase&PKD-1 (9)
- STAT&Axl (9)
- TGF-beta&Smad (15)
- VEGFR&EGFR (42)
- DNA&RNA Synthesis (20)
- ERK&JNK (11)
- Gamma Secretase (12)
- GPCR&G protein (51)
- Histone Methytransferase (19)
- HIV&HCV Protease (13)
- Wnt&Beta catenin (2)
- Other (0)