Showing 1–12 of 21 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|1253952-02-1||AR-13324 Hydrochloride (1253952-02-1)||
AR-13324 hydrochloride is a ROCK, and norepinephrine transporter inhibitor.AR-13324 Hydrochloride (Netarsudil) is a Rho kinase inhibitor with...
|1422144-42-0||AR-13324 mesylate (1422144-42-0)||
AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive mon...
|170364-57-5||Enzastaurin (LY317615) (170364-57-5)|
Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6-to 20-fold selectivity against PKCα, PKCγ and PKCε….
|105628-07-7||Fasudil hydrochloride (105628-07-7)||
Fasudil Hcl(HA-1077; AT-877) is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, ...
Bisindolylmaleimide I (GF109203X) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor with a Ki value of 1...
Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ withIC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKC...
|850664-21-0||GSK269962A (GSK269962) (850664-21-0)||
GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays ...
|223645-67-8||K-115 (free base) (223645-67-8)|
Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of19 and 51 nM for ROCK2 and ROCK1, respectively….
KD025 is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60nM and 41 nM, respectively…..
|1192189-69-7||LX7101 HCL (1192189-69-7)||
LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively; also inhibits ...
LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch clevage with withIC50 of...
MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2….
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