Showing 1–12 of 55 results

CAS NO. PRODUCT NAME OVERVIEW
    1166227-08-2 A66 (1166227-08-2)

    A66 is a highly specific and selective p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoform...

    870281-34-8 Acalisib (GS-9820) (870281-34-8)

    Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide...

    648450-29-7 AS-605240 (648450-29-7)

    AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα, respective...

    1236699-92-5 AS703026 (1236699-92-5)

    AS703026 (Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lin...

    1173900-37-2 AZD6482 (S-isomer) (1173900-37-2)

    AZD6482 (S-isomer) (1173900-37-2) is a potent and selective inhibitor of PI 3-kinase ß (PI3-Kß)with IC50 of 10 nM, 8-, 87- and 109-fold more ...

    1009298-09-2 AZD8055 (1009298-09-2)

    AZD8055 is a potent, ATP-competitive inhibitor of mTOR kinase with IC50 of 0.8 nM with excellent selectivity (∼1,000-fold) against PI3K isofo...

    BEZ235 (NVP-BEZ235) (915019-65-7)

    BEZ235 (NVP-BEZ235) is a potent dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM/5 nM/7 nM/75 ...

    944396-07-0 BKM120 (944396-07-0)

    BKM120 is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTO...

    1217486-61-7 BYL719 (1217486-61-7)

    BYL719, also known as, is an alpha-specific PI3K inhibitor being studied as an experimental drug to treat some cancers.

    870281-82-6 CAL-101 (Idelalisib) (870281-82-6)

    CAL-101, also known as Idelalisib and GS-1101 is a phosphoinositide 3-kinase inhibitor, which was developed by Gilead Sciences. It’s a ...

    1276105-89-5 CNX-1351 (1276105-89-5)

    CNX-1351 is a selective covalent Inhibitor of PI3Kα with IC50 value of 6.8 nM was 20−400 times less potent against β, γ, and δ. CNX-1351 inhi...

    1159824-67-5 CZC24832 (1159824-67-5)

    CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3...

1 2 3 4 5