Showing 1–12 of 80 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|5142-23-4||3-Methyladenine (3-MA) (5142-23-4)||
3-Methyladenine is an inhibitor of class III phosphatidylinositol 3-kinase (PI 3-kinase).It can protect cerebellar granule cells from apoptos...
A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.A-769662 displays selectivity towards β...
A66 is a highly specific and selective p110α inhibitor with IC50 of 32 nM, >100 fold selectivity for p110α over other class-I PI3K isoform...
|870281-34-8||Acalisib (GS-9820) (870281-34-8)||
Acalisib, also known as GS-9820, is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide...
AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks, with potential clinical anti-i...
AS-605240 selectively inhibits PI3Kγ with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3Kγ than PI3Kδ/β and PI3Kα, respective...
AS703026 (Pimasertib) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lin...
|1173900-37-2||AZD6482 (S-isomer) (1173900-37-2)||
AZD6482 (S-isomer) (1173900-37-2) is a potent and selective inhibitor of PI 3-kinase ß (PI3-Kß)with IC50 of 10 nM, 8-, 87- and 109-fold more ...
AZD8055 is a potent, ATP-competitive inhibitor of mTOR kinase with IC50 of 0.8 nM with excellent selectivity (∼1,000-fold) against PI3K isofo...
AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM), with potential antineoplastic activity.
|1032568-63-0||BAY80-6946 (Copanlisib) (1032568-63-0)||
BAY 80-6946 is a selective and ATP-competitive class-I PI3 kinases inhibito with sub-nanomolar IC₅₀s against PI3Kα and PI3Kδ. BAY 80-6946 dis...
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