A brake is a metalworking machine that allows the bending of sheet metal.

Showing 1–12 of 13 results

CAS NO. PRODUCT NAME OVERVIEW
    30827-99-7 AEBSF HCL (30827-99-7)

    AEBSF or 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride is a water-soluble, irreversible serine protease inhibitor with a molecular w...

    1361224-53-4 AMG-3969 (1361224-53-4)

    AMG-3969 is a potent, metabolically stable Glucokinase (GK)-GKRP (GK regulatory protein) disruptor with IC50 of 4 nM, does not block the GK b...

    1177827-73-4 AP-III-a4 (1177827-73-4)

    AP-III-a4 (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.

    80306-38-3 AR7 (80306-38-3)

    AR-7, also known as Atypical retinoid 7 , is a potent and selective enhancer of thechaperone-mediated autophagy (CMA).

    357263-13-9 BMS378806 (357263-13-9)

    BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.

    947620-48-6 E6005 (947620-48-6)

    E-6005, also known as RVT-501 and lotamilast, is a phosphodiesterase 4 (PDE-4) inhibitor potentially for the treatment of atopic dermatitis.<...

    928134-65-0 LCI699 (928134-65-0)

    LCI699, also known as Osilodrostat, is a potent inhibitor of 11β-hydroxylase, the enzyme which catalyzes the final step of cortisol synthesis...

    173039-10-6 PMPA (NAALADaseinhibitor) (173039-10-6)

    PMPA is a selective inhibitor of NAALADase with Ki value of 275 pM.PMPA is a potent NAALADase inhibitor and has a more activity than reported...

    1103926-82-4 TM5275 (1103926-82-4)

    TMS5275 is an orally available, potent and selective inhibitor of PAI-1 that delivers antithrombotic benefits devoid of bleeding effect in no...

    1190221-43-2 TM5441 (1190221-43-2)

    TM5441 is a plasminogen activator inhibitor-1 (PAI-1); inhibits several tumor cell lines with IC50 values between 9.7 and 60.3 μM.

    1000025-07-9 Vadadustat (1000025-07-9)

    Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of an...

    1345098-78-3 XMD16-5 (1345098-78-3)

    XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.

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