Showing 1–12 of 29 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC₅₀ = 3.3 nM). It displays >1000-fold selectivity for...
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other ace...
|1163-36-6||Clemizole HCL (1163-36-6)||
Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. The IC50 of Clemizole for ...
CPI-1205 is an orally available selective inhibitor of the histone lysine methyltransferase EZH2, with potential antineoplastic activity....
EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 ...
EPZ015666 is a potent, selective PRMT5 inhibitor (Ki of 5 nM); displays >20,000-fold selectivity over other PMTs. EPZ015666 acts by blocki...
|1616391-87-7||EPZ015866 (GSK591) (1616391-87-7)||
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase PRMT5/MEP50 complex thus stopping the methylation of his...
EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.
Pinometostat, also known as EPZ-5676. Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid...
Tazemetostat (EPZ-6438) is a potent, selective and orally available EZH2 inhibitor. Tazemetostat has been used in trials studying the treatme...
|1373423-53-0||GSK J4 (1373423-53-0)||
GSK-J4 has been used to study the effect of KDM2B (Jumonji (JmjC) domain histone 3 lysine 36 (H3K36) di-demethylase) inhibition on the surviv...
|1431368-48-7||GSK-LSD1 2HCl (1431368-48-7)||
GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used a...
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