Have you ever wondered what it means when you go to the store and look at al.

Showing 1–12 of 29 results

CAS NO. PRODUCT NAME OVERVIEW
    1527503-11-2 A-366 (1527503-11-2)

    A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC₅₀ = 3.3 nM). It displays >1000-fold selectivity for...

    328968-36-1 C646 (328968-36-1)

    C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other ace...

    1163-36-6 Clemizole HCL (1163-36-6)

    Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. The IC50 of Clemizole for ...

    1621862-70-1 CPI-1205 (1621862-70-1)

    CPI-1205 is an orally available selective inhibitor of the histone lysine methyltransferase EZH2, with potential antineoplastic activity.

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    1396772-26-1 EPZ005687 (1396772-26-1)

    EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 ...

    1616391-65-1 EPZ015666 (1616391-65-1)

    EPZ015666 is a potent, selective PRMT5 inhibitor (Ki of 5 nM); displays >20,000-fold selectivity over other PMTs. EPZ015666 acts by blocki...

    1616391-87-7 EPZ015866 (GSK591) (1616391-87-7)

    EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase PRMT5/MEP50 complex thus stopping the methylation of his...

    1700663-41-7 EPZ020411 (1700663-41-7)

    EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.

    1380288-87-8 EPZ5676 (1380288-87-8)

    Pinometostat, also known as EPZ-5676. Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid...

    1403254-99-8 EPZ6438 (1403254-99-8)

    Tazemetostat (EPZ-6438) is a potent, selective and orally available EZH2 inhibitor. Tazemetostat has been used in trials studying the treatme...

    1373423-53-0 GSK J4 (1373423-53-0)

    GSK-J4 has been used to study the effect of KDM2B (Jumonji (JmjC) domain histone 3 lysine 36 (H3K36) di-demethylase) inhibition on the surviv...

    1431368-48-7 GSK-LSD1 2HCl (1431368-48-7)

    GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used a...

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