Showing 1–12 of 13 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|714971-09-2||AC480 (BMS-599626) (714971-09-2)||
AC480, also known as BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced So...
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively..
|1187594-09-7||Baricitinib (LY3009104, INCB028050) (1187594-09-7)||
Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fo...
BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=11±7 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an...
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B ...
STK321130, also known as FLT3-IN-2, is potent FLT3 inhibitor.
Not Intended for Therapeutic Use. ...
G-749 is a novel and potent FLT3 inhibitor with IC50 of 0.4 nM, 0.6 nM and 1 nM for FLT3 (WT), FLT3 (D835Y), and Mer, respectively, showing l...
GSK503 inhibits the methyltransferase activity of WT and mutant EZH2 with similar potency. In a panel of seven DLBCL cell lines, GSK503 cause...
|501919-59-1||NSC 74859 (S3I-201) (501919-59-1)||
S3I-201, also known as NSC 74859, is a cell-permeable Stat3 inhibitor that binds to the Stat3-SH2 domain, prevents Stat3 phosphorylation/acti...
|950769-58-1||Quizartinib (AC220) (950769-58-1)||
Quizartinib is under investigation in Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies.Quizartinib is an orally available small mo...
|941678-49-5||Ruxolitinib (INCB018424) (941678-49-5)||
Ruxolitinib is a Janus kinase inhibitor that is used in the treatment of intermediate or high risk myelofibrosis. Ruxolitinib is associated w...
- PARP&Proteasome (22)
- Akt &GSK-3 (37)
- ATM&ATR (36)
- Bcl-2&P53 (11)
- c-Kit&c-Met (25)
- CDK&Aurora kinase (36)
- Chk&Rho (8)
- HDAC&PLK (0)
- HER2&FLT3 (13)
- IGF-1R&ALK (21)
- JAK&Bcr-Abl (4)
- MEK&P38 MAPK (22)
- PDGFR&FGFR (20)
- PI3K&mTOR (80)
- PKC&ROCK (21)
- Raf&HSP (29)
- S6 kinase&PKD-1 (9)
- STAT&Axl (9)
- TGF-beta&Smad (15)
- VEGFR&EGFR (42)
- DNA&RNA Synthesis (20)
- ERK&JNK (11)
- Gamma Secretase (12)
- GPCR&G protein (53)
- Histone Methytransferase (29)
- HIV&HCV Protease (27)
- Wnt&Beta catenin (17)
- Other (0)