Showing 1–12 of 25 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
|1345847-93-9||Altiratinib (DCC-2701) (1345847-93-9)||
Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, ce...
AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor. AMG-337 is a potent and highly selective...
AMG 458 is a potent c-Met inhibitor with Ki of 1 nM ~ 2.0 nM. AMG-458 was found to significantly inhibit tumor growth in the NIH3T3/TPR-Met a...
Motesanib (AMG-706), is an orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib ...
|850879-09-3||Amuvatinib (MP470) (850879-09-3)||
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC₅₀ values of 10 nM, 40 nM and 81 nM, respective...
|1021950-26-4||B-Raf inhibitor (1021950-26-4)||
Tyrosine-kinase inhibitor is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activatio...
BMS-794833 is active by greater than 50% tumor growth inhibition for at least one tumor doubling time in the GTL-16 gastric carcinoma model. ...
BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibitor of MET tyrosine kinase with potential an...
|877399-52-5||Crizotinib (PF2341066) (877399-52-5)||
Crizotinib, also known as PF-02341066, is an orally bioavailable agent belonging to the class of c-met/hepatocyte growth factor receptor (HGF...
PDGFR inhibitor 1 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of KIT and PDGFR with potential an...
|849217-64-7||Foretinib (GSK1363089) (849217-64-7)|
Foretinib, also known as XL880 and GSK1363089, is an orally bioavailable small molecule with potential antineoplastic activity.
|928037-13-2||Golvatinib (E7050) (928037-13-2)||
Golvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (va...
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