Showing 1–12 of 36 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase...
(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2),binding to all bromodomains of the BET family, but not to brom...
AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM...
Andarine is a selective non-steroidal androgen receptor (AR) agonist with Ki of 4 nM, tissue-selective for anabolic organs….
AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR. AZ20 is an ATR protein kinase i...
AZD0156 is an oral, potent and selective ATM kinase inhibitor, inhibiting the kinase activity of ATM and ATM-mediated signaling, preventing D...
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μMand has ability of reducing AR protein expression…
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR)...
AZD6738 is a potent selective oral ATR inhibitor. It can inhibit ATR substrate Chk1 Ser345 phosphorylation in cells with an IC50 value of 74 ...
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM. It is equally potent against Chk2 and less potent against CAM, Yes, Fy...
|847499-27-8||CEP-18770 (Delanzomib) (847499-27-8)||
CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of...
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM. CGK733 is an ATM inhibitor and ATR inhibitor, which significantl...
- PARP&Proteasome (22)
- Akt &GSK-3 (37)
- ATM&ATR (36)
- Bcl-2&P53 (11)
- c-Kit&c-Met (25)
- CDK&Aurora kinase (36)
- Chk&Rho (8)
- HDAC&PLK (0)
- HER2&FLT3 (13)
- IGF-1R&ALK (21)
- JAK&Bcr-Abl (4)
- MEK&P38 MAPK (22)
- PDGFR&FGFR (20)
- PI3K&mTOR (80)
- PKC&ROCK (21)
- Raf&HSP (29)
- S6 kinase&PKD-1 (9)
- STAT&Axl (9)
- TGF-beta&Smad (15)
- VEGFR&EGFR (42)
- DNA&RNA Synthesis (20)
- ERK&JNK (11)
- Gamma Secretase (12)
- GPCR&G protein (53)
- Histone Methytransferase (29)
- HIV&HCV Protease (27)
- Wnt&Beta catenin (17)
- Orther (1)