Showing 1–12 of 36 results

CAS NO. PRODUCT NAME OVERVIEW
    856925-71-8 (-)-Blebbistatin (856925-71-8)

    (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase...

    1268524-70-4 (+)-JQ1 (1268524-70-4)

    (+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2),binding to all bromodomains of the BET family, but not to brom...

    659730-32-2 AMG517 (659730-32-2)

    AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM...

    401900-40-1 Andarine (401900-40-1)

    Andarine is a selective non-steroidal androgen receptor (AR) agonist with Ki of 4 nM, tissue-selective for anabolic organs….

    1233339-22-4 AZ20 (1233339-22-4)

    AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM, 8-fold selectivity over mTOR. AZ20 is an ATR protein kinase i...

    1821428-35-6 AZD0156 (1821428-35-6)

    AZD0156 is an oral, potent and selective ATM kinase inhibitor, inhibiting the kinase activity of ATM and ATM-mediated signaling, preventing D...

    1240299-33-5 AZD3514 (1240299-33-5)

    AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μMand has ability of reducing AR protein expression…

    1035270-39-3 AZD4547 (1035270-39-3)

    AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR)...

    1352226-88-0 AZD6738 (1352226-88-0)

    AZD6738 is a potent selective oral ATR inhibitor. It can inhibit ATR substrate Chk1 Ser345 phosphorylation in cells with an IC50 value of 74 ...

    860352-01-8 AZD7762 (860352-01-8)

    AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM. It is equally potent against Chk2 and less potent against CAM, Yes, Fy...

    847499-27-8 CEP-18770 (Delanzomib) (847499-27-8)

    CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of...

    905973-89-9 CGK733 (905973-89-9)

    CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM. CGK733 is an ATM inhibitor and ATR inhibitor, which significantl...

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