Showing 1–12 of 37 results
|CAS NO.||PRODUCT NAME||OVERVIEW|
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 value...
|1047634-63-8||Afuresertib (GSK2110183) (1047634-63-8)||
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Aktinhibitor with IC50s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 r...
AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM, without significant inhibition on 26 ot...
AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity; AKT, p70S6K, PKA, ROCK, and SGK inhib...
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little a...
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respective...
AZD2858 is a potent and GSK-3 inhibitor with an IC50 of 68 nM. AZD-2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt s...
AZD5363, also known as Capivasertib, is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with pote...
Bikinin(Abrasin) is a potent inhibitor of plant GSK-3/Shaggy-like kinase; activates BR signaling downstream of the BR receptor.
CH5132799 inhibits class I PI3Ks, particularly PI3Kα with IC50 of 14 nM; less potent to PI3Kβδγ, while sensitive in PIK3CA mutations cell lin...
CHIR-98014 is a selective GSK3 inhibitor with IC50s of 0.65 nM and 0.58 nM for GSK-3α and GSK-3β; potentiate insulin activation of glucose tr...
|915019-65-7||Dactolisib (BEZ235) (915019-65-7)||
BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110/// and mTOR(p70S6K) with IC50 of 4 nM/5 nM/7 nM/75 nM/6 nM, re...
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