What is Anandamide (AEA)

Anandamide (AEA), also known as the bliss molecule, or N-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter. The name Anadamida (AEA) is derived from the Sanskrit of Joy “Ananda.” Raphael Mechoulam coined the term. How, along with his two assistants, W. A. Devane and Lumír Hanuš, first discovered “Anandamide” in 1992. Anandamide (AEA) is a great fix for a lot of our physical and mental problems. 

 

How Anandamide (AEA) Works

Anandamide(AEA) is derived from the non-oxidative metabolism of eicosatetraenoic acid. Anandamide (AEA) is a lipid mediator and functions as an endogenous ligand of CB1 receptors and modulates its reward circuitry. It is an important neurotransmitter in the endocannabinoid system, named after Cannabis. It helps regulate the flow of neurochemical systems to keep your body and mind functioning smoothly. It is found that the Anandamide structure is similar to tetrahydrocannabinol (THC), the main psychotic component of Cannabis. Thus Anandamide changes mood simulates what popularly is known as Cannabis high.

It is naturally produced in our body as per the brain’s instruction by a condensation reaction in neurons. The condensation reaction controlled by calcium ion and cyclic monophosphate adenosine takes place between arachidonic acid and ethanolamine. 

Anandamide increases happiness by interacting with cannabinoid receptors in the nervous and peripheral nervous system, CB1 and CB2. CB1 receptors target Motor activity (movement) and coordination, Thinking, Appetite, Short terms memory, Pain perception, and Immunity. At the same time, CB2 receptors target major organs like the Liver, Gut, kidney, Pancreas, Adipose tissues, Skeletal muscle, Bone, Eye, Tumours, Reproductive system, Immune system, Respiratory tract, skin, Central Nervous system, and Cardiovascular system.

In our body, N-arachidonoylethanolamine breaks down into fatty acid amide hydrolase (FAAH) enzyme and produces arachidonic acid and ethanolamine. If FAAH’sFAAH’s action can be slowed down, we can reap Anandamide’sAnandamide’s benefits for a longer period.

Anandamide (AEA)

Anandamide (AEA) benefits

Anandamide(AEA) simulates the effects of Cannabis on our system, without its adverse effects. Anandamide helps us by stimulating our brain function in the following ways:

  1. Enhancing brain capacity and memory

Enhancing your working memory capacity is a major Anandamide (AEA) benefits. It also helps you become more creative by processing information into new ideas. A study in mice has shown significant improvement in brain function. Thus if you want to improve your analytical skills, creative skills, or do well in your studies, Anandamide is the perfect solution.

  1. Acts as an appetite controller

If you want to follow a strict diet, appetite control is a must. One of the Anandamide benefits is it can help you control appetite and satiety cycles. You can easily control the pangs of hunger or cravings for junk with the help of Anandamide. This way, you can achieve your weight loss targets or targets of regaining shape. In the modern days staying healthy and fit largely depends on our food habits, and Anandamide supplements can help us. But the weight loss plans with Anandamide should be complemented with proper dietary plans. Severe undereating can lead to a sudden loss of body weight and, thus, metabolic problems. Also, in the case of lactating mothers, Anandamide consumption needs to be avoided.

  1. Neurogenesis

One way to increase your brain function capacity is to have new neurons or brain cells through Neurogenesis. This is true, especially you are nearing 40 or have gone beyond the age. Anandamide (AEA) helps in Neurogenesis.

Moreover, higher levels of Anandamide levels in the human body eradicate the risks of neurodegenerative diseases like Perkinson’sPerkinson’s disease, etc. At the old age, Anandamide helps in recovery from neurodegeneration related problems like memory loss, depression, fear, lack of control on the body, etc. Anandamide (AEA) helps older adults enjoy their retired life without worrying about their health issues.

  1. Controlling Sexual Desires

Anandamide (AEA) benefits control your sexual desire in two ways. In mild dosage, it enhances sexual desires. But with the heavy dose of Anandamide (AEA) reduces the sexual urge. Anandamide (AEA) improves your mood and relieves stress giving rise to the sexual urge. But a higher dose makes you sexually satisfied, and you find no need for sexual activity.

  1. Anti-Cancer properties

Anandamide (AEA) has ant carcinogenic properties through psychotropic effects. Anandamide (AEA) fights cancerous tissue growth. It is especially beneficial in breast cancer. Experiments are showing that it can be a good replacement for conventional drugs of cancer. Moreover, it is free of any side effects compared to the life-changing effects of conventional cancer drugs. Thus shortly, a large scale acceptance of Anandamide (AEA) might alleviate the pain that cancer patients go through during the treatment. 

  1. Antiemetic properties

Nausea and vomiting can also be controlled with Anandamide (AEA). It works with serotonin to control nausea. This makes Anandamide (AEA) an antiemetic solution during chemotherapy on cancer patients. This can be good for pregnant mothers also. But in the case of pregnant mothers, Anandamide (AEA) should be done only if recommended by her physician.

  1. Pain Relief properties

By bonding with CB1, Anandamide (AEA) blocks the transmission of pain signals. This way, Anandamide (AEA) can be used for chronic pain relief in patients suffering from medical conditions like gout, arthritis, or sciatica. In older ages, pain is a constant companion. Anandamide (AEA) is a proven remedy for migraines and other severe headaches. Consumption of Anandamide (AEA) supplements in old age may help them win over pain and will also improve their quality of life.

  1. Mood Regulator

The endocannabinoid system controls our mood. Anandamide (AEA) controls our negative mind states like fear, anxiety, and increases happiness. This way, Anandamide (AEA) can function as a mood up-lifter, improve mental health, and improve your inner being. As Anandamide (AEA) supplements are non-addictive, it is highly recommended, especially for the working-age population, who need to continue working with high productivity in a very demanding and stressful environment.

  1. To fight off depression

Anandamide (AEA) can also fight off depression. A study on mice recently proved its antidepressant properties. Depression and related problems are taking a toll on our mental and physical health … even in our society. Addiction to nicotine, alcohol, drug abuse is often linked with depression. Even more severe conditions may lead people to take their lives. Depression can be a debilitating negative force that can even lead people to death. Anandamide (AEA) can be a great solution to this problem.

  1. Fights off Inflammation and Edema

Anandamide (AEA) reduces cell swelling and edema. This way, it is also useful as an anti-inflammatory solution.

  1. Improves Fertility

Anandamide (AEA) can play a beneficial role in ovulation and implantation. Studies show that high Anandamide (AEA) levels ensure successful ovulation.

  1. Solves Hyper-Tension and Kidney dysfunction

More than 60% of people will develop hypertension or chronic kidney diseases. Anandamide (AEA)can modulate kidney functions that cause the disease. Anandamide (AEA)has shown good results in solving problems caused by elevated blood pressure. 

 

Anandamide (AEA) Natural Sources

  • Essential Fatty Acids

Eggs, Chia seeds, flax seeds, sardines, hemp seeds are great sources of endocannabinoid enhancing fatty acids. In turn, this improves the level of Omega 3 and Omega 6 in our body improve endocannabinoid activity.

  • Tea and Herbs

Cannabis, cloves, cinnamon, black pepper, oregano, etc. improve Anandamide levels in our bodies. Tea is a very good source of Anandamide (AEA).

  • Chocolate

Dark chocolate is one of the best sources of Anandamide. Cocoa powder is made up of oleolethanolamine and linoleoylethanolamine. The lower the breakdown of endocannabinoids and thus maintain the Anandamide levels in our body. Also, chocolate has theobromine, which helps Anandamide production.

  • Black Truffles (black fungi)

Black Truffles contains natural Anandamide.

 

Anandamide (AEA) supplements and other ways to improve Anandamide levels

  • CBD (Cannabidiol)

One of the best ways to stimulate the endocannabinoid system is the consumption of CBD. CBD is the major source of medical marijuana. CBD inhibits FAAH and thus improves Anandamide levels in our body. 

  • Exercise

Exercise brings in a feel-good factor in us. Exercise improves Anandamide levels in the body and thus increase your tendency to exercise harder. Experiments show that after exercise, they become calm and immune to pain. This is supposed because of CB1 and CB2’sCB2’s activation by Anandamide. It is seen 30 minutes of intense running or aerobics significantly increases the Anandamide levels in our bodies. It is also seen that migraines patients who take up aerobics tend to recover from the same. It is mainly because of the high levels of Anandamide produced in their body due to the heavy exercise.

  • Stress Reduction

People who can control stress have a higher level of Anandamide in them. Stress decreases CB1 receptors’ effect and thus reduces the levels of Anandamide and, in turn, show reduced cannabinoid function. Thus avoid stressful situations to improve overall wellbeing. One such solution is meditation.

Mediation improves both Anandamide and dopamine levels in our body. Mediatbodiesleads to higher levels of oxytocin which further enhances Anandamide levels in our body. It’s like a good cycle of wellbeing. Anandamide helps you calm down and meditate; meditation further enhances your Anandamide levels and helps you get relief from stress.

Anandamide (AEA)

 

Anandamide (AEA) Dosage

Like other endocannabinoids, the low external dosage of Anandamide is good for us. High doses are detrimental to our bodies. 1.0mg/kg. (per Kg of body weight) is an appropriate dosage of Anandamide (AEA). But if you are finding any problems, you must consult a physician immediately. In pregnant mothers and mothers who are breastfeeding they must consult their physicians before Anandamide (AEA) usage. 

 

Anandamide (AEA) Side Effects

Anandamide has high tolerance and low side effects. You may experience some temporary difficulties like weight loss, dizziness, or vomiting. In certain cases, Anandamide (AEA) administration during breastfeeding (studied on adult mice) leads to weight gain, body fat accumulation, and even insulin resistance. This happens due to increased appetite leading to high food consumption.

 

Buying  Anandamide (AEA) Supplements

We can easily understand to live a healthy life Anandamide (AEA) is essential. It helps in prevention and fighting off different ailments. To avoid Anandamide (AEA) deficiency, it is wise to consume supplements in the prescribed dosage. Generally, Anandamide (AEA) is available in oil (70% and 90%) and Powder forms (50%). China has become the major producer of Anandamide (AEA) supplements.

 

Where to buy Anandamide (AEA) powder in bulk

Cofttek   product

Established in 2008, Cofttek is a high-tech Dietary Supplement company from Luohe City, Henan Province, China.

  • Package: 25kg/ drum

Hope this helps!! What are you waiting for then?  Get Anandamide home and make life easier!

 

References
  1. Mallet PE, Beninger RJ (1996). “The endogenous cannabinoid receptor agonist anandamide impairs memory in rats”. Behavioural Pharmacology. 7 (3): 276–284
  2. Mechoulam R, Fride E (1995). “The unpaved road to the endogenous brain cannabinoid ligands, the anandamides”. In Pertwee RG (ed.). Cannabinoid receptors. Boston: Academic Press. pp. 233–
  3. Rapino, C.; Battista, N.; Bari, M.; Maccarrone, M. (2014). “Endocannabinoids as biomarkers of human reproduction”. Human Reproduction Update. 20 (4): 501–516.
  4. ANANDAMIDE (AEA) (94421-68-8)

 

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